ʻO ka ʻike ʻana a me ka laha ʻana o nā ʻano mutant Omi Keron

1. Ka ʻike ʻana a me ka laha ʻana o Omi Keron mutant strains Ma Nowemapa 9, 2021, ua ʻike ʻo ʻApelika Hema i kahi ʻano B.1.1.529 o ka coronavirus hou mai kahi laʻana hihia no ka manawa mua. I loko o 2 mau pule wale nō, ua lilo ka mutant strain i ka mana nui loa o nā hihia maʻi kalaunu hou ma Gauteng Province, South Africa, a ua wikiwiki kona ulu ʻana. Ma Nowemapa 26, ua wehewehe ka WHO iā ia ʻo ka ʻelima o ka "variant of concern" (VOC), i kapa ʻia ʻo ka leka Helene ʻo Omicron (Omicron). Ma ka lā 28 o Nowemapa, ua nānā ʻo ʻApelika Hema, Israel, Belgium, Italia, United Kingdom, Austria, a me Hong Kong, Kina, i ka hoʻokomo ʻana o ka mutant strain. ʻAʻole i loaʻa ka hoʻokomo o kēia ʻano mutant ma nā panalāʻau a me nā kūlanakauhale ʻē aʻe o koʻu ʻāina. Ua ʻike mua ʻia ka mutant Omi Keron a hōʻike ʻia ma ʻApelika Hema, akā ʻaʻole ia he manaʻo ua ulu ka maʻi ma ʻApelika Hema. ʻO kahi i loaʻa ai ka mutant ʻaʻole ia kahi i kumu.

2. ʻO nā kumu kūpono paha o ka hiki ʻana mai o nā mutants Omi Keron E like me ka ʻike i hōʻike ʻia e ka ʻikepili lei aliʻi hou GISAID, ʻoi aku ka nui o nā pūnaewele mutation o ka virus korona hou ʻO Omi Keron mutant strain ʻoi aku ka nui ma mua o nā maʻi kalaunu hou a pau. mutant strains i kaapuni i nā makahiki ʻelua i hala iho nei, ʻoi aku hoʻi i ka hoʻololi ʻana o ka protein spike (Spike). . Manaʻo ʻia ʻo nā kumu o kona puka ʻana mai ʻekolu mau kūlana: (1) Ma hope o ka loaʻa ʻana o ka mea maʻi immunodeficiency i ka maʻi coronavirus hou, ua loaʻa iā ia kahi manawa lōʻihi o ka evolution i loko o ke kino e hōʻiliʻili i ka nui o nā mutations. ua hoʻouna ʻia ma ka manawa kūpono; (2) kekahi maʻi hui holoholona ʻO ka coronavirus hou, ke hele nei ka maʻi maʻi i ka adaptive evolution i ka wā o ka laha ʻana o ka heluna holoholona, ​​a ʻoi aku ka kiʻekiʻe o ka mutation ma mua o ko ke kanaka, a laila kahe i loko o ke kanaka; (3) Ua hoʻomau ka neʻe ʻana o kēia mutant strain no ka manawa lōʻihi i nā ʻāina a i ʻole nā ​​​​wahi kahi e lohi nei ka nānā ʻana o ka mutation o ka genome coronavirus hou. , Ma muli o ka lawa ʻole o ka mākaʻikaʻi ʻana, ʻaʻole hiki ke ʻike ʻia nā maʻi maʻi waena o kona hoʻomohala ʻana i ka manawa.

3. Hiki ke ho'ouna 'ia o Omi Keron mutant strain I kēia manawa, 'a'ohe 'ikepili noi'i ma'amau e pili ana i ka ho'ouna 'ana, pathogenicity, a me ka hiki 'ole ke pakele o Omi Keron mutants i ka honua. Eia nō naʻe, loaʻa i ka ʻano ʻokoʻa ʻo Omi Keron kekahi mau pūnaewele mutation amino acid i nā ʻano ʻano mua ʻehā VOC Alpha, Beta, Gamma a me Delta spike proteins, me ka hoʻonui ʻana i nā cell receptors. Nā kahua hoʻololi no ka pilina somatic a me ka hiki ke hoʻopili hou i nā virus. Hōʻike ka ʻikepili o ka maʻi epidemiological a me ka nānā ʻana i ka ʻikepili i ka nui o nā hihia o nā ʻano ʻokoʻa Omi Keron ma ʻApelika Hema, ua hoʻonui nui ʻia, a ua hoʻololi ʻia i nā ʻano ʻano Delta (Delta). Pono e nānā hou ʻia ka mana hoʻouna.

4. ʻO ka hopena o ka Omi Keron varit strain i nā lāʻau lapaʻau a me nā lāʻau antibody Ua hōʻike nā haʻawina i ka hiki ʻana mai o nā hoʻololi K417N, E484A, a i ʻole N501Y i loko o ka protein S o ka coronavirus hou e hōʻike ana i kahi hiki ke pakele i ka pale; ʻoiai ʻo ka Omi Keron mutant he triple mutation o “K417N+E484A+N501Y”; Eia kekahi, ʻo ka Omi Keron mutant kekahi He nui nā hoʻololi ʻē aʻe e hōʻemi i ka hana neutralizing o kekahi mau antibodies monoclonal. Hiki i ka superposition o nā mutations ke hōʻemi i ka pono pale o kekahi mau lāʻau antibody e kūʻē iā Omi Keron mutants, a ʻo ka hiki i nā lāʻau lapaʻau e pakele i ka pale ʻana e pono ai ka nānā ʻana a me ka noiʻi.

5. E pili ana anei ka Omi Keron i ka nucleic acid detection reagents i kēia manawa ma koʻu ʻāina? Ua hōʻike ʻia ka loiloi genome o ka Omi Keron mutant strain ʻaʻole pili kona kahua mutation i ka naʻau a me ka kikoʻī o nā reagents ʻike nucleic acid i koʻu ʻāina. ʻO nā pūnaewele mutation o ka Omi Keron mutant strain ka mea nui loa i ka ʻāpana ʻokoʻa loa o ka S protein gene, a ʻaʻole i loaʻa i ka nucleic acid detection reagent primers a me nā wahi i hoʻopaʻa ʻia i paʻi ʻia i ka ʻewalu o ka paʻi o koʻu ʻāina "New Coronavirus Pneumonia. Ka Papahana Kāohi a me ka Manaʻo "(Kina ʻO ka ORF1ab gene a me N gene i hoʻokuʻu ʻia e nā Centers for Disease Control and Prevention i ka honua). Eia naʻe, hōʻike ʻia nā ʻikepili mai nā laboratories he nui ma ʻApelika Hema, ʻaʻole hiki i nā reagents detection acid nucleic i ʻike i ka gene S ke ʻike pono i ka moʻo S o ka ʻano ʻano Omi Keron.

6. Nā ana i lawe ʻia e nā ʻāina a me nā ʻāpana pili I ka nānā ʻana i ke ʻano wikiwiki o ka maʻi ahulau o Omi Keron mutants ma ʻApelika Hema, nui nā ʻāina a me nā ʻāpana, me ʻAmelika Hui Pū ʻIa, United Kingdom, European Union, Russia, Israel, Taiwan a me koʻu ʻāina. Ua kaupalena ʻo Hong Kong i ke komo ʻana o ka poʻe huakaʻi mai ʻApelika Hema.

7. ʻO ka pane ʻana o koʻu ʻāina ʻO ka hoʻolālā pale a me ka hoʻomalu ʻana o ko mākou ʻāina ʻo "pale i waho, pale kūloko kūʻē i ka hoʻihoʻi ʻana" ʻoi aku ka maikaʻi e kūʻē i ka mutant Omi Keron. Ua hoʻokumu ka Institute of Viral Diseases of the Chinese Center for Disease Control and Prevention i kahi ʻano ʻike kikoʻī nucleic acid no ka Omi Keron mutant strain, a ke hoʻomau nei i ka mālama ʻana i ka genome viral no nā hihia i lawe ʻia mai. ʻO nā hana i ʻōlelo ʻia ma luna nei e maʻalahi ka ʻike ʻana i nā mutants Omi Keron i hiki ke lawe ʻia mai i koʻu ʻāina.

8. Nā ʻōlelo aʻoaʻo a WHO no ka pane ʻana iā Omi Keron mutant strains Ua paipai ʻo WHO i nā ʻāina e hoʻoikaika i ka mākaʻikaʻi, hōʻike a me ka noiʻi ʻana o ka coronavirus hou, a e hana i nā hana olakino olakino e hoʻōki i ka laha ʻana o ka maʻi; ʻO nā mea e pale ai i ka maʻi maʻi i ʻōlelo ʻia no kēlā me kēia kanaka, ʻo ia ka mālama ʻana i kahi mamao ma kahi o 1 mika ma nā wahi ākea, ke ʻaʻahu ʻana i nā masks, ka wehe ʻana i nā puka makani no ka ea, a me ka mālama ʻana i ka hoʻomaʻemaʻe ʻana i kou mau lima, ka ʻū a i ʻole ke kihe ʻana i kou kuʻekuʻe a i ʻole ka ʻiʻo, hoʻopaʻa ʻia, etc. pale aku i ka hele ʻana i nā wahi ʻino ʻole a i ʻole nā ​​​​hui kanaka. Ke hoʻohālikelike ʻia me nā ʻano ʻokoʻa VOC ʻē aʻe, ʻaʻole maopopo ʻia inā ʻoi aku ka ikaika o ka hoʻoili ʻana o ka Omi Keron, pathogenicity a me ka hiki ke pakele. E loaʻa i ka noiʻi kūpono nā hopena mua i nā pule e hiki mai ana. Akā ʻo ka mea i ʻike ʻia i kēia manawa, hiki i nā maʻi mutant ke kumu i ka maʻi nui a i ʻole ka make, no laila ʻo ka pale ʻana i ka laha ʻana o ka maʻi maʻi ke kī mau, a ʻo ka lāʻau lei aliʻi hou e hoʻemi i ka maʻi nui a me ka make.

9. I ke alo o ka ʻano hou o ka coronavirus hou ʻO Omi Keron, he aha ka mea e pono ai ka lehulehu e makaʻala i kā lākou hana i kēlā me kēia lā? (1) He ala maikaʻi loa ka hoʻohana ʻana i ka mask no ka pale ʻana i ka laha ʻana o ka maʻi maʻi, a pili pū nō hoʻi ia i nā maʻi ʻo Omi Keron mutant. ʻOiai inā ua hoʻopau ʻia ka papa holoʻokoʻa o ka hoʻomaʻamaʻa ʻana a me ka hoʻoikaika ʻana, pono nō hoʻi e ʻaʻahu i ka mask ma nā wahi ākea o loko, ka halihali lehulehu a me nā wahi ʻē aʻe. Eia kekahi, e holoi pinepine i kou mau lima a e hoʻoluliluli i ka lumi. (2) Hana maikaʻi i ka nānā ʻana i ke olakino pilikino. Ke loaʻa nā hōʻailona o ka maʻi maʻi maʻi coronary hou, e like me ke kuni, ka ʻū, ka pōkole o ka hanu a me nā hōʻailona ʻē aʻe, e nānā koke i ka wela o ke kino a lawe i ka manaʻo e ʻike i ke kauka. (3) E ho'ēmi i ke komo 'ana a me ka puka 'ana. I nā lā liʻiliʻi wale nō, ua hōʻike ʻia nā ʻāina a me nā ʻāina he nui i ka lawe ʻia ʻana mai o nā ʻano mutant Omi Keron. Ke kū nei ʻo Kina i ka pilikia o ka lawe ʻana mai i kēia maʻi mutant, a ua kaupalena ʻia ka ʻike honua o kēia ʻano mutant. No laila, pono e hoʻemi ʻia ka huakaʻi i nā wahi pilikia nui, a pono e hoʻoikaika ʻia ka pale pilikino i ka wā o ka huakaʻi e hōʻemi ai i ka loaʻa ʻana o ka maʻi me Omi Keron mutant strains.